Clinical Reasoning: A 12-year-old boy with ascending weakness

Clinical Reasoning: A 48-year-old woman with generalized weakness.

Chafic Karam, MD Stephen N. Scelsa, MD SECTION 1 A 48-year-old woman was referred to the neuromuscular clinic because of progressive generalized weakness for 4 months. Her symptoms started after she had a thyroidectomy and radioactive iodine treatment for a thyroid papillary carcinoma. She had proximal arm weakness when washing her hair and had trouble climbing steps and getting out of her chai...

Clinical reasoning: encephalopathy in a 10-year-old boy.

Lance Rodan, MD Ingrid Tein, MD, FRCPC SECTION 1 A 10-year-old, right-handed boy with a several-day history of fever and upper respiratory symptoms presented with acute onset headache, emesis, progressive mental status change, and right-sided focal seizures. Symptoms developed over approximately 3 hours. There was no history of recent toxic or medication exposures, travel, immunizations, sick c...

A 12-year-old boy with increasing verbal aggression.

A 12-Year-Old Boy with Pars Planitis.

A 12-year-old boy with renal failure and haemoptysis

A 12-year-old boy, previously well, presented with increasing pallor, lethargy and intermittent gross haematuria for 1 month. He also had a history of haemoptysis for the previous 5 days. His blood pressure was normal and he had pedal oedema. There was no hepatosplenomegaly, joint swelling or skin rash. Laboratory investigations (Table 1) revealed anaemia, hypoalbuminaemia and elevated serum cr...